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What are the long-term prospects for dogs on doxepin

My 6-yr-old St. Bernard, Olympia, was diagnosed on Thursday w/larngeal collapse and we were told the only help was a permanent trach.

After researching this site and others, I read about Doxepin. My vet prescribed it that night (Olympia was also on a sedative and prednisone)…by Saturday I had reduced the pred and eliminated the sedative (something was giving her awful diarrhea) and by Monday she was breathing almost normally, sleeping a lot, but getting up, going outside, wagging her tail and demanding attention!

She is not 100 percent her old self, but she’s very far from death’s door, which is where she stood on Thursday. I think this drug is a miracle!

Anyway, I have not been able to find any information about the long-term prospects for dogs on doxepin. Will she be sleepy forever? Will it work for a long time?

What is the quality of life for dogs on doxepin?

Thanks for any help!



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9 Responses to “What are the long-term prospects for dogs on doxepin”

  1. Taylor - Blog Administrator says:

    Hello Valle,

    While I could not find any references to long term prospects for dogs on doxepin, here are some usage notes for the drug when prescribed by a veterinarian:

    · Precautions and Side Effects
    · While generally safe and effective when prescribed by a veterinarian, doxepin may cause unacceptable side effects in some animals.
    · Doxepin should not be used in animals with known hypersensitivity or allergy to the drug.
    · Doxepin should not be used in animals with glaucoma or those with medical problems that are associated with urinary retention.
    · Doxepin should be used with caution in seizure-prone animals.
    · Side effects include: low blood pressure, high blood pressure, rapid heart rate, constipation, and dry mouth.
    · Doxepin sometimes turns urine blue-green in color.
    · Doxepin may interact with some other medications. Consult your veterinarian to determine if other medications that your pet is receiving might adversely interact with doxepin. Such drugs include: monoamine oxidase inhibitors, thyroid medications, atropine, sedatives, antihistamines, norepinephrine, and phenytoin.

    Let’s see if our pet pros have any answer to your question…….

    Blog Administrator

  2. admin says:

    Thanks again Taylor!

    I’ll be eagerly checking for other responses.
    My dog continues to do well and I really feel like she was pulled from the brink of death…I’m so happy!

  3. Cindi says:

    I’m not sure about dogs, but I’ve taken doxepin every day for 15 years. My doctor says it’s extremely safe and has no long term side effects.

  4. Tammy says:

    Valle, How is your dog doing on Doxepin? My vet just prescribed it for my lil Morkie Sadie and she seems really dopey after she takes it… Just wanted to see how your dog was doing

  5. DEBBIE says:

    hI, mY DOG WAS DIAGNOSED WITH A PARTIALLY COLLAPSED TRACHEA. (Sorry for the cap lock). Yesterday I gave her her 1st dose of Doxepin. Her breathing seems better but she seems sleepy and less playful. Well, my vet says the reasons are not known how this drug helps this condition but people say it does. Before she took it she would be up all night unable to breath comfortably. The thing that scares me is that she is on Thyriod medication and I just saw someone say these 2 drugs may not mix so I have to talk to the vet about it. Until someone gives me another safe option, I will give her this med. Its better then not being able to breath.

  6. DEBBIE says:

    Ugh where is my mind today. I meant to say my dog was diagnosed with a partially paralyzed larynx. Im sorry, I had a dog with a collapsed trachea and I typed the wrong thing. My dog Brownie who is a chocolate lab has the partially paralyzed larynx and truthfully im a nervous wreck as I love her very much and It hurts me to see she cant breath good. Today she choked on a milk bone. Anyhow, im hoping the Doxepin works for her.

  7. Kim says:

    My dog has the tie-back surgery did this and has done very well for a few years. Today the dr started him on doxipin. Hoping he has good results. I know the surgery to tie back the paralyzed part gave him a few more years of quality. He is 13, black lab.

  8. Donna says:

    My lab has been on doxepin for almost a week. He is only 6 and half and has polyneuropathy, diagnosed with laryngeal paralysis almost three years ago, diagnosed with neuropathy in hind legs almost two. I do not want to do surgery as he has been through too much already.
    The Doxepin is clearly helping although I am not sure for how long. Any folks with a year or two experience?

  9. Darby says:

    My 12 year old lab has larynx issues and trouble breathing. The vet has recommended doxepin, but she has had seizures in tenge last and I see this listed as a possible problem. Anyone experienced issues with a dog who has had past seizures? She is not on any seizure meds

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